We collect locations of functional pockets from enzymes To estimateĭensities of ?xed charge, we measure the volume of functional pockets and count We imagine that electric charge plays important roles, becauseĮven one charge in a small space produces large electric ?elds. Here, we look for biological properties of that Functional pockets mix catalytic amino acidsĪnd substrate in tiny volumes. The chemistry of enzymes occurs at active sites that concentrate biologicalįunction into functional pockets.
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